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Publications
REFEREED PUBLICATIONS
Andrew Hong, Aiying Zhang, Yang Ke, Abdeslem El Idrissi and Chang-Hui Shen. (2011)
Downregulation of GABAA b subunits is transcriptionally controlled by
Fmr1p. J. Mol. Neurosci. (in press; PMID:21547530)
Roshini
N. Wimalarathna, Chen-Han Tsai and Chang-Hui Shen. (2011)
Comparative transcriptional analysis of genes involved in yeast phospholipid
biosynthesis. J. Microbiol.
49, 265-273.
Michelle Esposito, Paulina Konarzewska, Oluwafemi Odeyale, and Chang-Hui Shen
(2010) Activator-dependent
recruitment of histone acetylation at the yeast INO1 promoter. Biochem Biophys
Res Commun 391, 1285-1290.
Aiying Zhang, Chang-Hui Shen,
Shuang Yong Ma, Yang Ke,
and Abdeslem El Idrissi (2009) Altered expression of Autism-associated genes in the brain of
Fragile X mouse model. Biochem Biophys
Res Commun 379, 920-923.
Jason Ford, Oluwafemi Odeyale, and Chang-Hui Shen (2008) Activator-dependent recruitment of SWI/SNF and INO80 during INO1 activation. Biochem Biophys
Res Commun.
373, 602-626.
Jason Ford, Oluwafemi Odeyale, Antonious Eskandar, Nafila Kouba, and Chang-Hui Shen
(2007) A SWI/SNF- and
INO80-dependent nucleosome movement at the INO1
promoter. Biochem Biophys Res Commun 361, 974-979.
David Clark and
Chang-Hui Shen. (2006) Mapping histone modifications by
nucleosome immunoprecipitation. Methods in Enzymology,
410, 416-430.
Geetu Mendiratta , Peter R. Eriksson , Chang-Hui Shen and
David Clark. (2006) The DNA-binding domain of the yeast Spt10
activator includes a zinc finger that is homologous to foamy virus integrase. J. Biol. Chem. 281, 7040-7048.
Peter R. Eriksson, Geetu Mendiratta, Neil
McLaughlin, Tyra Wolfsberg,
Leopoldo Maríño-Ramirez,
Tiffany Pompa, Mohendra Jainerin, David Landsman, Chang-Hui Shen and David J. Clark (2005) The putative histone acetyltransferase encoded by the yeast SPT10 gene binds specifically to upstream activating sequences in
the major core histone promoters Mol. Cell. Biol. 25, 9127-9137.
Yeonjung Kim, Chang-Hui Shen and David Clark.(2004) Purification
and Nucleosome Mapping Analysis of Native Yeast Plasmid Chromatin. Methods. 33, 59-67.
Chang-Hui Shen, Benoit P.
Leblanc, Carolyn Neal, Ramin Akhaven and David J.
Clark. (2002). Targeted histone acetylation at
the yeast CUP 1 promoter requires the
transcriptional activator, the TATA boxes, and the putative histone acetylase
encoded by SPT10. Mol. Cell. Biol. 22, 6406-6416.
Chang-Hui Shen, Benoit Leblanc,
Jennifer Alfieri and David Clark. (2001) Remodeling of the
yeast CUP 1 chromatin involves
activator-dependent re-positioning of nucleosomes over the entire gene and
flanking sequences. Mol. Cell. Biol. 21:
534-547.
Chang-Hui Shen and David Clark, (2001) DNA sequence plays a major role in
determining nucleosome positions in yeast chromatin. J. Biol. Chem. 276:35209-3516.
BOOK
Chang-Hui
Shen (2011)
Histones: Class, Structure and Function, Nova Science Publisher, Inc. NY.
BOOK CHAPTERS
Chang-Hui Shen (2011)
Linker histones and chromatin structure. In: Chang-Hui Shen. Histones: Class, Structure and Function,
Nova Science Publisher, Inc. NY. (in press)
Roshini
Wimalarathna and Chang-Hui Shen (2011) Histone modifications and gene
expression. In: Chang-Hui Shen.
Histones: Class, Structure and Function, Nova Science Publisher, Inc. NY. (in press)
CONFERENCE ABSTRACTS
Eugene Lempert and Chang-Hui Shen. Cloning of the
critical domains of Ino2p responsible for recruiting chromatin remodeling
activities. CSI undergraduate
conference, NY, 2011.
Roshini
Wimalarathna, Po Yun Pan and Chang-Hui Shen. Transcriptional regulation of yeast CUP1 gene. Biochem. Cell Biol. (in press) (abstract)
Roshini
Wimalarathna, Po Yun Pan and Chang-Hui Shen. Transcriptional regulation of yeast CUP1 gene. 32nd
International conference – Asilomar Chromatin and
Chromosome Conference. CA, 2010.
Michele Esposito, Paulina
Konarzewska, and Chang-Hui Shen. Histone acetylation at the yeast INO1 promoter requires the
transcriptional activator and both Gcn5p and Esa1p histone acetylase. CSI undergraduate conference, NY, 2009.
Jason Ford and
Chang-Hui Shen. SWI/SNF
and INO80 Contribute to Local Nucleosome Mobilization at the INO1
Promoter. CSI undergraduate conference, NY, 2008.
Chang-Hui Shen,
Jason Ford and Oluwafemi Odeyale. The role of romatin remodeling activities in INO1 activation. Symposium on biological complexity:
diseases of transcription. Salk Institute, San Diego, CA. 2007.
Tiffany Pompa, Jonathan Blaize, William L’Amoreaux and Chang-Hui
Shen. Correlation
between Methylation and Acetylation within the Cell
due to Environmental Factors. Microscopy
and Microanalysis 2006 Meeting.
Chicago.
Tiffany Pompa, Jonathan Blaize, William L’Amoreaux and Chang-Hui
Shen. Co-localization of the putative histone acetylase Spt10p
and chemically modified histone H3.
Microscopy and Microanalysis 2005 Meeting. Honolulu,
Hawaii.
Oluwafemi Odeyale and Chang-Hui Shen.
The interplay between histone modifying enzyme and
chromatin remodeling complex in INO1
activation. New York City
Louis Strokes Alliance for Minority
Participation Conference, Steven’s Institute
of Technology in New Jersey, 2005.
Oluwafemi Odeyale and Chang-Hui Shen.
The role of chromatin remodeling complex in yeast INO1 gene expression. National
conference & research symposium, 2005,
Stony Brook, awarded First Place for poster in the biological
sciences.
Oluwafemi Odeyale and Chang-Hui Shen.
The role of chromatin remodeling complex in yeast INO1 gene expression. Annual
Biomedical Research Conference for Minority Students, Dallas, TX, 2004, pp.280.
Oluwafemi Odeyale and Chang-Hui Shen.
The role of chromatin remodeling complex in yeast INO1 gene expression. New York City
Louis Strokes Alliance
for Minority Participation Conference, Brookhaven National Laboratory, 2004.
Antonious Eskandar, Nafila Kouba, Oluwafemi Odeyale, Baishali Kanjilal and Chang-Hui Shen. In Vivo Chromatin Remodeling by Yeast Ino80p. The 69th Cold
Spring Harbor
Symposium on Quantitative Biology.
Cold Spring Harbor, NY. 2004, pp.58.
Chang-Hui Shen and David Clark. Histone Hyperacetylation
at the CUPI Promoter Requires the
Transcriptional Activator and the TATA Boxes.
Keystone Symposia - Mechanisms of Eukaryotic Transcriptional Regulation,
Santa Fe, NM 2001, pp. 90.
Chang-Hui Shen, Benoit Leblanc,
Jennifer Alfieri and David Clark.
Chromatin Structure of a Transcriptionally Active Metallothionein Gene
Purified from yeast Cells, Keystone Symposia - Chromatin Structure and
Function. Durango, CO, 2000,
pp.72.
Chang-Hui Shen and James Allan.
Expression of the Chicken Linker Histone Globular Domain in E. coli is
Post-Transcriptionally Regulated. The Biochemical Society Predoctoral
Meeting, Glasgow Caledonian
University, Glasgow, UK,
1996. Biometra Prize for the Best Poster.